Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2008 Jul 7;205(7):1621–1634. doi: 10.1084/jem.20071365

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2008 GeurtsvanKessel et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jem.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 1. — Number and surface phenotype of mouse lung CD11b⁺ and CD11b⁻ DCs, pDCs, and alveolar macrophages after influenza infection. Populations were gated as shown in Fig. S2 (available at http://www.jem.org/cgi/content/full/jem.20071365/DC1) and as indicated by the gates in the left column of each panel. (A) CD11b⁺ DCs significantly increased after infection and remained increased up to 10 dpi (left). CD86 expression was plotted in histograms (right), with MFI shown in the graph (bottom). (B) The increase in CD11b⁻ DCs is demonstrated in flow cytometric plots (left), with absolute numbers shown in the graph (bottom). CD86 expression was up-regulated and plotted as MFI (C, bottom). pDCs increased significantly at 2 dpi and then returned to baseline. Recruitment of pDCs was accompanied by up-regulation of CD86 (right). (D) Alveolar macrophages slightly increased in number, but CD86 expression was not increased. Gray histograms represent isotype controls and were measured at 4 dpi. The values are representative of five mice per group and are expressed as mean ± SEM. Similar results were obtained from at least three separate experiments. *, P < 0.05; **, P < 0.01.