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. 2008 Jul 7;205(7):1621–1634. doi: 10.1084/jem.20071365

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© 2008 GeurtsvanKessel et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jem.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 7. — Virus-specific serum antibodies of influenza virus–infected mice after DC subset depletion. (A) Virus-specific antibodies in the serum of C57BL/6 mice after i.p. treatment with 120G8 depleting antibody or PBS, or (B) in the serum of CD11c-DTR mice after i.t. treatment with DT or PBS, measured at 8 dpi and 1 mo after infection. The values are representative of at least five mice per group and are expressed as geometric mean titer (GMT) of HI ± SEM. The differences in HI titer can be explained by the background of the mice. CD11c-DTR mice were F1 (BALB/c × C57BL/6) animals and developed less high viral and HI titers than the pure C57BL/6 mice that were used in 120G8 depletion experiments. Similar results were obtained from at least two separate experiments. *, P < 0.05; **, P < 0.01.