TABLE 1.
Strain | N | Liver TG mg/gm | Liver CHOL mg/gm | Serum TG mg/dL | Serum CHOL mg/dL |
---|---|---|---|---|---|
Female | |||||
BALB-apoB+/+ | 38 | 123 (44)bC | 13.1 (1.7)bC | 86 (27)A | 61 (15)aA |
BALB-apoB+/38.9 | 55 | 243 (57)aA | 16.4 (2.7)aA | 88 (33)A | 42 (14)bC |
C57-apoB+/+ | 39 | 79 (26)bD | 14.4 (2.3)bBC | 56 (20)B | 64 (12)aA |
C57-apoB+/38.9 | 49 | 157 (29)aB | 16.3 (2.4)aA | 61 (28)B | 50 (10)bBC |
SWR-apoB+/+ | 12 | 46 (23)bE | 14.3 (1.5)bBC | 97 (29)A | 56 (10)aAB |
SWR-apoB+/38.9 | 21 | 101 (29)aCD | 15.7 (2.2)aAB | 90 (29)A | 32 (14)bD |
Male | |||||
BALB-apoB+/+ | 23 | 132 (41)bBC | 13.2 (1.5)BC | 106 (30)A | 85 (21)aA |
BALB-apoB+/38.9 | 49 | 287 (130)aA | 14.7 (2.6)AB | 93 (38)AB | 66 (23)bB |
C57-apoB+/+ | 41 | 74 (28)bCD | 12.6 (2.0)C | 74 (23)B | 74 (15)AB |
C57-apoB+/38.9 | 24 | 151 (44)aB | 13.9 (2.1)ABC | 76 (20)B | 71 (9)AB |
SWR-apoB+/+ | 10 | 36 (14)bD | 14.2 (1.7)ABC | 84 (18)AB | 68 (21)AB |
SWR-apoB+/38.9 | 12 | 62 (27)aD | 15.2 (1.3)A | 89 (19)AB | 60 (8)B |
1 Plasma and hepatic lipids were assessed using commercial methods described in 10. Liver triglyceride and cholesterol were expressed as mg/g liver protein. Results are means (SD).
2 The low-case superscript in each column (a and b) indicated significant difference (α = 0.01) between apoB genotype (apoB+/+ vs apoB+/38.9) within each genetic background (BALB, C57, or SWR). The upper-case superscript in each column (A, B etc) indicated the results of multiple comparisons among means of all congenics (Duncan's multiple range test, α = 0.01).