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Thermodynamic constants of CBR1 V88 and CBR1 I88 derived from microcalorimetry titration analyses with NADPH
| CBR1 V88 | CBR1 I88 | |
|---|---|---|
| Kda (μM) | 3.8 ± 0.5 | 6.3 ± 0.6 |
| Kaa × 105 M−1 | 2.6 ± 0.2 | 1.6 ± 0.2 |
| ΔH (kcal/mol) | −29 ± 1 | −29 ± 1 |
| ΔG (kcal/mol) | −52 ± 1 | −51 ± 1 |
| TΔS (kcal/mol) | −20 ± 1 | −21 ± 1 |
Differences between CBR1 variant isoforms were significant at p < 0.001.
