Table 1.
Associations (χ2-tests/Fischers exact test) between the protein expression of ADAM9 in renal cell cancer and clinico-pathological parameters (percentages in brackets)
| Total | low ADAM9 | high ADAM9 | p-value | |
| All cases | 108 (100) | 71 (65.7) | 37 (34.3) | |
| Age | 0.225 | |||
| ≤ 62 | 59 (54.6) | 42 (71.2) | 17 (28.8) | |
| > 62 | 49 (45.4) | 29 (59.2) | 20 (40.8) | |
| Histology | < 0.001 | |||
| Clear cell | 86 (79.6) | 65 (75.6) | 21 (24.4) | |
| chromophobe | 5 (4.6) | 2 (40.0) | 3 (60.0) | |
| Papillary | 17 (15.7) | 4 (23.4) | 13 (76.5) | |
| pT-status | 0.104 | |||
| pT1 | 54 (50.0) | 40 (74.1) | 14 (25.9) | |
| pT2/3/4 | 54 (50.0) | 31 (57.4) | 23 (42.6) | |
| pN-status* | 0.022 | |||
| pN0 | 51 (47.2) | 36 (70.6) | 15 (29.4) | |
| pN1 | 12 (11.1) | 4 (33.3) | 8 (66.7) | |
| Grading | 0.002 | |||
| G 1 | 11 (10.2) | 11(100) | 0 (0) | |
| G 2 | 75 (69.4) | 50 (66.7) | 25 (33.3) | |
| G 3/4 | 22 (20.4) | 10 (45.5) | 12 (54.5) | |
| Residual tumour status# | 0.073 | |||
| R0 | 78 (72.2) | 56 (71.8) | 22 (28.2) | |
| R1/2 | 15 (13.9) | 7 (46.7) | 8 (53.3) | |
| Metastasis | 0.014 | |||
| M0 | 85 (78.7) | 61 (71.8) | 24 (28.2) | |
| M1 | 23 (21.3) | 10 (43.5) | 13 (56.5) |
* 45 cases were pNx
# 15 cases were Rx