Table 2.
Paralogous ribosomal protein genes exhibit different phenotypes. Phenotypic data for all ribosomal proteins was mined from published datasets; a representative sample is shown. Sensitivity is indicated by “1” unless otherwise indicated.
| RPL7 | RPL12 | RPL13 | RPL20 | RPL27 | RPL34 | RPL41 | RPP1 | RPS4 | RPS10 | RPS14 | RPS30 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A | B | A | B | A | B | A | B | A | B | A | B | A | B | A | B | A | B | A | B | A | B | A | B | |
| Bud-site Selection*,A | 1 | 2 | 2 | 2 | 2 | |||||||||||||||||||
| Cell Size#,B | 1 | 1 | 1 | 1 | 2 | 1 | ||||||||||||||||||
| Sporulation & MeiosisX,C | 1 | 2 | 2 | 2 | ||||||||||||||||||||
| Repressed by MMSD | 1 | 1 | 1 | |||||||||||||||||||||
| Vacuolar Protein SortingΛ,E | 2 | 2 | 2 | 1 | 1 | 2 | ||||||||||||||||||
| Wortmannin Sensitivity+,F | 2 | 4 | 3 | 2 | 2 | 1 | −2 | 2 | 3 | 1 | 2 | 2 | 2 | −3 | ||||||||||
| Caffeine Sensitivity+,G | 1 | 1 | 1 | 1 | ||||||||||||||||||||
| Cycloheximide Sensitivity+,G | 2 | 3 | ||||||||||||||||||||||
| Sulfometuron Methyl Sensitivity+,G | 1 | 2 | ||||||||||||||||||||||
| Rapamycin Sensitivity+,H | 3 | 4 | ||||||||||||||||||||||
| Abnormal Telomere Length,∇,J | −2 | −2 | −3 | 1 | 2 | 2 | ||||||||||||||||||
| Neomycin Sulfate SensitivityK | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | ||||||||||||||||
| Pentamidine SensitivityK | 1 | 1 | 1 | |||||||||||||||||||||
| Hydrogen Peroxide SensitivityK | 1 | 1 | 1 | 1 | 1 | |||||||||||||||||||
| Mitomycin SensitivityK | 1 | 1 | ||||||||||||||||||||||
| Trichostatin A SensitivityK | 1 | 1 | 1 | |||||||||||||||||||||
| Benomyl SensitivityK | 1 | 1 | 1 | |||||||||||||||||||||
| Phenantroline SensitivityK | 1 | 1 | ||||||||||||||||||||||
| Hygromycin B SensitivityK | 1 | 1 | 1 | |||||||||||||||||||||
| Desipramine SensitivityK | 1 | 1 | 1 | |||||||||||||||||||||
| CG4-Theopalaumide SensitivityK | 1 | 1 | ||||||||||||||||||||||
| Caspofungin SensitivityK | 1 | 1 | 1 | |||||||||||||||||||||
| Basiliskamide SensitivityK | 1 | 1 | ||||||||||||||||||||||
| Papuamide SensitivityK | 1 | 1 | ||||||||||||||||||||||
| Geldanamycin SensitivityK | 1 | 1 | 1 | |||||||||||||||||||||
1=strong defect, 2=weak defect
1=among the smallest 5%, 2=among the largest 5%
1=low sporulation efficiency, 2=high sporulation efficiency but reduced number of spores per ascus
1=strong or moderate defect, 2=weak defect
“-“ indicates resistance; higher number indicates higher sensitivity/resistance
1=slightly long, 2=long, 3=very long, −1=slightly short, −2=short, −3=very short
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