Figure 8.

Amino acid sequence of PLA₂ isolated from Crotalus durissus cascavella and its estimated secondary structure. The calcium binding loop, active site and C-terminal region are present in the sequence. Note the highly conserved calcium binding loop and active site, and an extensive portion of basic amino acid residues, such as Arg and Lys, in the C-terminal. This PLA₂ showed high homology with other PLA₂s, such as the isoforms from Crotalus durissus terrificus (Cdt F15, F16 and F17). Crotoxin B (cloned basic subunit of crotoxin) and mojave b (PLA₂ subunit of Crotalus scutulatus scutulatus).