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. 2008 Jul 1;6(7):e161. doi: 10.1371/journal.pbio.0060161

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© 2008 Figueiredo et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Examples of four nondividing bloodstream cells expressing HA-RPB6z, detected by HA.11 monoclonal antibody. DNA was detected with DAPI (blue). Scale bar: 2 μm.

(B) Quantification of cells containing 0, 1, or 2 extranucleolar spots in parental and ΔDOT1B double-expresser (DE) HA-RPB6z clones. The total number of cells and the percentage in each category is indicated for three independent experiments. The average values from the three experiments are shown as a histogram.