Table 1.
Genotypic and allelic distributions of two SNPs in BMP-2 gene between OPLL patients and non-OPLL Controls
| SNPs | Ser37Ala (T/G) | Ser87Ser (A/G) | ||||
|---|---|---|---|---|---|---|
| Genotype | TT | TG | GG | AA | AG | GG |
| OPLL (n = 57) | 38 | 19 | 0 | 1 | 15 | 41 |
| Control (n = 135) | 126 | 9 | 0 | 0 | 23 | 112 |
| Fisher’s exact test | P < 0.001 | P = 0.081 | ||||
| Allele | T | G | A | G | ||
| OPLL | 95 | 19 | 17 | 97 | ||
| Control | 261 | 9 | 23 | 247 | ||
| Fisher’s exact test | P < 0.001 | P = 0.069 | ||||
Note: Difference in genotypic and allelic distribution between subpopulation of OPLL patients and controls were analyzed using χ 2-test