Table 3.

Secondary outcomes, influence of manipulation, clinical prediction rule and interaction on pain and disability

	Pain	P value	Disability (RMDQ)	P value
1 week
SMT	0.013 (−0.826 to 0.852)	0.976	−1.753 (−3.853 to 0.348)	0.102
Rule status	−0.693 (−1.462 to 0.076)	0.077	−1.802 (−3.749 to 0.144)	0.069
SMT × rule status	0.308 (−0.781 to 1.396)	0.578	1.763 (−0.970 to 4.496)	0.205
2 weeks
SMT	−0.455 (−1.330 to 0.420)	0.306	−2.669 (−4.782 to −0.556)	0.014
Rule status	−0.995 (−1.796 to −0.193)	0.015	−2.139 (−4.101 to −0.178)	0.033
SMT × rule status	0.114 (−1.021 to 1.248)	0.843	2.378 (−0.381 to 5.136)	0.091
4 weeks
SMT	−0.113 (−0.823 to 0.597)	0.754	−1.501 (−3.307 to 0.306)	0.103
Rule status	−0.540 (−1.191 to 0.110)	0.103	−1.625 (−3.301 to 0.052)	0.057
SMT × rule status	−0.215 (−1.135 to 0.705)	0.645	1.081 (−1.268 to 3.431)	0.366
12 weeks
SMT	−0.208 (−0.969 to 0.554)	0.592	−1.751 (−3.622 to 0.120)	0.066
Rule status	−0.367 (−1.066 to 0.333)	0.303	−2.164 (−3.901 to −0.428)	0.015
SMT × rule status	0.051 (−0.934 to 1.036)	0.919	2.314 (−0.120 to 4.747)	0.062

Results of linear regression models for pain and disability. For both pain and disability, negative values represent improved outcomes. Results regarding the ability of the prediction rule to identify patients who respond most to SMT are presented in the line SMT × rule status

RMDQ Roland Morris disability questionnaire, SMT spinal manipulative therapy