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. Author manuscript; available in PMC: 2008 Jul 4.
Published in final edited form as: J Pathol. 2007 Sep;213(1):91–98. doi: 10.1002/path.2207

Table 2.

FGFR3 mutations identified

Exon Nucleotide change Amino acid change Number of mutations Frequency of mutation (%)
7 c.742C>T1 R248C 8 11.3
7 c.746C>G S249C 34 47.9
10 c.1114G>T G372C 5 7.1
10 c.1117A>T S373C 1 1.4
10 c.1124A>G Y375C 16 22.5
10 c.1144G>A G382R 2 2.8
10 c.1178C>A A393E 1 1.4
15 c.1954A>C K652E 3 4.2
15 c.1954A>G K652Q 1 1.4
1

nucleotide position according to the FGFR3b isoform numbering from the initiating ATG