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. Author manuscript; available in PMC: 2008 Jul 4.
Published in final edited form as: J Pathol. 2007 Sep;213(1):91–98. doi: 10.1002/path.2207

Table 3.

Association of FGFR3 expression levels and presence of mutation

GRADE/STAGE1 Low FGFR3 expression High FGFR3 expression Total P value (Fisher’s exact test)
wildtype mutant wildtype mutant
1 2 (17%) 1 (8.3%) 2 (16.7%) 7 (58.3%) 12 0.2364
2 9 (16%) 5 (9.0%) 9 (29.3%) 32 (58.2%) 55 0.007
3 34 (47.4%) 3 (4.2%) 21 (29.2%) 14 (19.4%) 72 0.0019
Ta 13 (19.4%) 7 (10.5%) 9 (13.4%) 38 (56.7%) 67 <0.0001
T1 11 (42.3%) 0 4 (15.4%) 11 (42.3%) 26 <0.0001
T2 19(48.7%) 2 (5.1%) 15 (38.5%) 3 (7.7%) 39 0.0012
1

Tumours in which staining was scored differently in different regions of the section (n=10 including one pTx sample) are not included