Table I.
Variable | Cases (N = 755) | Controls (N = 636) | P value |
n (%) | n (%) | ||
Age at recruitment (years) | 0.26 | ||
≤50 | 103 (13.7) | 103 (16.2) | |
51–60 | 221 (29.3) | 194 (30.5) | |
61–70 | 260 (34.4) | 219 (34.4) | |
>70 | 171 (22.6) | 120 (18.9) | |
Gender | 0.33 | ||
Female | 320 (42.4) | 253 (39.8) | |
Male | 435 (57.6) | 383 (60.2) | |
Race | 0.004 | ||
Non-Hispanic white | 649 (86.0) | 585 (92.0) | |
Hispanic | 47 (6.2) | 24 (3.8) | |
Black | 50 (6.6) | 21 (3.2) | |
Other | 9 (1.2) | 6 (1.0) | |
Family history of cancera | <0.001 | ||
No | 175 (23.3) | 197 (31.0) | |
Yes | 577 (76.7) | 438 (69.0) | |
History of diabetesb | <0.001 | ||
No | 567 (75.1) | 571 (90.0) | |
Yes | 188 (24.9) | 64 (10.0) | |
Smoking status | <0.001 | ||
Non-smokers | 304 (40.3) | 310 (48.7) | |
≤20 pack-years | 186 (24.6) | 166 (26.1) | |
>20 pack-years | 265 (35.1) | 160 (25.2) | |
Alcohol consumptionc | 0.345 | ||
Never | 334 (44.2) | 271 (43.6) | |
≤60 g/day | 362 (47.9) | 313 (50.4) | |
>60 g/day | 59 (7.9) | 37 (6.0) | |
CYP1A2*1Fd | 0.957 | ||
AA | 341 (52.5) | 307 (52.5) | |
AC | 276 (42.5) | 247 (42.2) | |
CC | 32 (4.9) | 31 (5.3) | |
Sult1A1 | 0.651 | ||
GG | 248 (38.2) | 228 (39.0) | |
GA | 368 (56.7) | 321 (54.9) | |
AA | 33 (5.1) | 36 (6.2) | |
NAT1 | 0.353 | ||
Non*10 | 431 (66.4) | 403 (68.9) | |
*10 | 218 (33.6) | 182 (31.1) | |
NAT2 | 0.797 | ||
Rapid | 38 (5.9) | 34 (5.8) | |
Intermediate | 248 (38.2) | 213 (36.4) | |
Slow | 363 (55.9) | 338 (57.8) |
Information was missing for three cases and one control because of adopted family.
Information was missing for one control.
Information was missing for 15 controls.
Distribution for non-Hispanic white.