Table 2.

Distribution of somatostatin and somatostatin receptor subtypes in animal and human kidney

	ss	sst1	sst2A	sst2B	sst3	sst4	sst5	References
Mouse
Distal tubules	+		+					Bates et al. 2003,2004a,b
Proximal tubules		+	+		+	+	+
Collecting ducts			+
Glomeruli		+	+			+	+
mRNA	+	+	+		+	+	+
Rat
Distal tubules								Kurokawa et al. 1983; Bruno et al. 1993; Kimura et al. 2001
Proximal tubules
Collecting ducts			+
Glomeruli	+		+
mRNA	+	+	+		+	±, +	±
Human
Distal tubules	+	+	+	+	+	+	+	Yamada et al. 1992; Rohrer et al. 1993; Turman et al. 1997; Turman and Apple 1998; Balster et al. 2001; Taniyama et al. 2005a
Proximal tubules	+	+	+	+	+	+	+
Collecting ducts	+	+	+	+	+	+	+
Glomeruli	+	+	+	+	+	+	+
mRNA	+	+	+	+	±,+	+	+

^aResults from this study.

ss, somatostatin; sst, somatostatin receptor subtypes; +, positive staining; ±, disputable.