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. Author manuscript; available in PMC: 2008 Nov 19.
Published in final edited form as: Vaccine. 2007 Oct 2;25(47):7984–7993. doi: 10.1016/j.vaccine.2007.09.030

Figure 1.

Figure 1

Serum anti-F1-V responses following SC immunization. Swiss Webster mice were immunized at day 0 and 28 subcutaneously with F1-V alone (F) or in conjunction with LT(R192G) (R), CpG ODN (C), MPL®TDM (M), or alum (A). Ten animals from each group were sacrificed on days 15, 30 and 60 post final immunization. Serum was collected by cardiac puncture. Concentrations of IgG (panels A, B and C), IgG1 (panels D, E and F) and IgG2a (panels G, H and I) were determined by ELISA by non-linear regression against standard curves. Error bars represent ± SEM. Adjuvant enhanced responses that are significantly different (p≤0.05) than antigen alone are indicated with an asterisk (*).