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. Author manuscript; available in PMC: 2008 Nov 19.
Published in final edited form as: Vaccine. 2007 Oct 2;25(47):7984–7993. doi: 10.1016/j.vaccine.2007.09.030

Figure 5.

Figure 5

Serum anti-F1-V responses following TC immunization. Swiss Webster mice were immunized at day 0 and 28 transcutaneously with F1-V alone (F) or in conjunction with LT(R192G) (R), CpG ODN (C), or MPL®TDM (M). Ten animals from each group were sacrificed on days 15, 30 and 60 post final immunization. Serum was collected by cardiac puncture. Concentrations of IgG (panels A, B and C), IgG1 (panels D, E and F) and IgG2a (panels G, H and I) were determined by ELISA by non-linear regression against standard curves. Error bars represent ± SEM. Adjuvant enhanced responses that are significantly different (p≤0.05) than antigen alone are indicated with an asterisk (*).