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. Author manuscript; available in PMC: 2008 Jul 7.
Published in final edited form as: Am J Physiol Gastrointest Liver Physiol. 2003 Jun 11;285(5):G967–G979. doi: 10.1152/ajpgi.00532.2002

Figure 3.

Figure 3

Recovery of transepithelial electrical resistance (A) and restitution (B) of Ussing chambered porcine ileal mucosa after deoxycholate injury and treatment with exogenous prostaglandins (PG) or indomethacin (INDO). PGE2 (10−6 M) and prostacyclin (10−6 M) or INDO (5×10−6M) were added immediately after injury and prior to onset of repair (time = 30-min). (A) INDO abolished recovery of TER while addition of exogenous PG resulted in an early elevation in TER that did not exceed baseline recovery at 210-min (✱ p<0.05 ✱✱ p<0.01 and ✱✱✱ p<0.001 –vs- injured control; one-way ANOVA). (B) Percent epithelialization of villi are shown at timepoints corresponding to maximal effects of exogenous PG (75-min) and INDO (210-min) on recovery of TER. Values represent mean ± SE; n= number of pigs; n.s. = not statistically significant.