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. Author manuscript; available in PMC: 2009 Jun 1.
Published in final edited form as: Virus Res. 2008 Feb 21;134(1-2):186–202. doi: 10.1016/j.virusres.2008.01.001

Table 2.

Common Regions for Superpositionings: MoMLV RT and HIV-1 RT

Domain or Subdomain MoMLV RT Residues HIV-1 RT Residuesa Secondary structure

Fingers/Palm 68–84 28–43 α-helix
194–214 155–175 α-helix
217–222 178–183 β-strand
225–230 186–191 β-strand
233–250 195–212 α-helix
264–269 225–230 β-strand
271–275 232–236 β-strand

Thumb 295–308 255–268 α-helix
312–315 273–276 β-strand
316–323 277–284 α-helix
343–356 299–312 α-helix

Connection 391–401 348–358 β-strand
411–427 366–382 α-helix
439–449 395–405 α-helix
452–457 408–413 β-strand

RNase H 519–528 438–447 β-strand
533–540 452–459 β-strand
547–552 463–468 β-strand
559–573 475–489 α-helix
577–582 492–497 β-strand
584–592 499–507 α-helix
615–626 516–527 α-helix
629–634 530–535 β-strand
648–657 544–553 α-helix
a

Common regions listed here are from PDB code 1HYS.

Other HIV-1 RT structures might contain more gaps, thus fewer of the representatives listed were used in those comparisons.

The 2HMI structure has its RNase H extended to residue 558.