TABLE 3.

Summary of kinetic properties and K_i values of the strains included in the study

Organism	Strain	FKS1-HS1 sequencea	Vmax (nmol/min)b	Km (mM)b	Ki (ng/ml)b
					ANF	CSF	MCF
C. parapsilosis	22019	FLTLSLRDA	0.52 ± 0.14	0.60 ± 0.16	639.50 ± 10.61	47.99 ± 0.72	476.00 ± 2.83
C. parapsilosis	H4	FLTLSLRDA	0.44 ± 0.16	0.45 ± 0.07	368.50 ± 13.44	3.93 ± 2.22	486.00 ± 7.07
C. parapsilosis	H5	FLTLSLRDA	0.46 ± 0.04	0.59 ± 0.05	431.67 ± 15.89	6.01 ± 0.71	261.00 ± 11.31
C. orthopsilosis	H10	FLTLSLRDA	0.33 ± 0.20	0.51 ± 0.07	111.00 ± 5.66	4.29 ± 1.11	177.50 ± 2.12
C. orthopsilosis	981224	FLTLSLRDA	0.40 ± 0.04	0.93 ± 0.11	46.50 ± 12.02	7.40 ± 2.69	248.00 ± 2.83
C. metapsilosis	am-2006-0113	FLTLSLRDA	0.18 ± 0.07	0.22 ± 0.13	41.40 ± 5.09	76.90 ± 0.85	266.00 ± 8.49
C. metapsilosis	960161	FLTLSLRDA	0.25 ± 0.20	0.20 ± 0.02	129.00 ± 11.31	80.45 ± 0.49	382.50 ± 2.12
S. cerevisiae	BY4742	FLVLSLRDP	2.65 ± 0.16	0.10 ± 0.02	68.95 ± 12.51	183.94 ± 35.27	179.01 ± 8.08
S. cerevisiae	BY4742-P649A	FLVLSLRDA	1.58 ± 0.13	0.13 ± 0.08	2374.0 ± 9.90	1215.00 ± 12.73	5706.50 ± 20.51
C. albicans	Sc5314	FLTLSLRDP	6.72 ± 0.25	0.12 ± 0.01	1.33 ± 0.56	2.97 ± 1.58	27.47 ± 1.82
C. albicans	90028	FLTLSLRDP	5.87 ± 0.20	0.09 ± 0.01	1.43 ± 0.14	0.95 ± 0.05	23.53 ± 2.37
C. albicans	36082	FLTLSLRDP	4.71 ± 0.48	0.07 ± 0.01	0.63 ± 0.18	0.46 ± 0.04	15.47 ± 2.05
C. albicans	M122	FLTLSLRDH	1.95 ± 0.29	0.15 ± 0.01	646.07 ± 26.72	291.67 ± 50.16	2588.53 ± 32.25
C. glabrata	90030	FLILSLRDP	6.97 ± 0.57	0.13 ± 0.01	16.15 ± 1.06	18.95 ± 3.04	1.13 ± 0.18
C. glabrata	T51916	FLILSLRDT	0.37 ± 0.06	0.05 ± 0.01	712.00 ± 9.90	194.50 ± 23.33	510.00 ± 67.88

^aFKS2-HS1 sequences are shown for C. glabrata strains. Substituted amino acids are in bold.

^bArithmetic means ± standard deviations (three repetitions).