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fT > MICs for corresponding EDs of BPR against all S. aureus isolates in an immunocompromised murine pneumonia model
| S. aureus strain | % fT > MIC for:
|
Maximum log10 CFU reduction | ||
|---|---|---|---|---|
| ED80 | ED50 | Stasis | ||
| MSSA 25923 | 10.2 | 8.1 | 7.6 | 4.2 |
| MSSA 29213 | 19.5 | 14.8 | 13.3 | 3.9 |
| HA-MRSA 56 | 15.5 | 13.7 | 13.1 | 3.9 |
| HA-MRSA 149 | 13.8 | 8.6 | 6.6 | 4.1 |
| HA-MRSA 152 | 15.9 | 14.0 | 13.4 | 3.8 |
| CA-MRSA 144 | 14.3 | 13.8 | 13.6 | 2.9 |
| CA-MRSA 146 | 6.0 | 5.5 | 5.6 | 3.6 |
| CA-MRSA 147 | 21.6 | 17.1 | 14.9 | 3.2 |
| Mean (SD) | 14.6 (4.9) | 11.9 (4.0) | 11.0 (3.7) | 3.7 (0.5) |
