Table 2.

Tear volume, corneal smoothness, corneal permeability, tear turnover rate, and conjunctival goblet cell density in 4-week-old untreated mice (4W), 16-week-old untreated mice (16W), and 16-week-old mice subjected to an air draft without (F) or with (FS) systemic scopolamine administration for 5 and 10 days (D) in the NOD.B10.H2^b mouse strain

	4W	16W	Group	5Da	10Da,b	p (F vs. FS)
	p (4W vs. 16W)
Tear volume (μL)	0.06±0.01	0.05±0.01	F	0.04±0.01	0.04±0.01	<0.01 in 5D
	<0.01		FS	0.03±0.01**	0.02±0.01***	<0.05 in 10D
Tear turnover rate (%)	5.21±1.93	3.28±1.54	F	3.15±1.61	1.31±0.52*†
	0.06		FS	2.03±1.10	1.05±0.41**
Corneal smoothness score	0.25±0.43	1.00±0.60	F	1.13±0.64	1.17±0.30	<0.05 in 5D
	<0.01		FS	2.13±1.13*	2.80±1.39**	<0.01 in 10D
Corneal permeability score	0.40±0.69	2.50±1.00	F	3.17±1.40	3.83±1.40*
	<0.01		FS	3.88±0.96**	4.83±0.94***†
Goblet cell density (cells/100 μm)	5.07±0.86	4.18±0.21	F	3.84±0.44	3.56±0.32**	<0.01 in 10D
	<0.05		FS	3.76±0.14**	2.82±0.34***††

^a*p<0.05,

^**p<0.01,

^***p<0.001 vs. 16W.

^{b †}p<0.05,

^††p<0.01,

^†††p<0.001 vs. 5D.