TABLE 2.
WT | CF | |||
---|---|---|---|---|
Mol%a | ||||
Saturated | ||||
16:0 | 16.95 ± 0.70 | 18.90 ± 0.80 | ||
18:0 | 16.35 ± 0.95 | 17.93 + 0.65 | ||
20:0 | 0.36 ± 0.06 | 0.17 ± 0.01c | ||
22:0 | 0.11 ± 0.02 | 0.08 ± 0.02 | ||
24:0 | 0.40 ± 0.14 | 0.06 ± 0.06 | ||
n-6 | ||||
18:2n-6 | 17.20 ± 0.91 | 12.61 ± 0.96c | ||
18:3n-6 | 0.25 ± 0.04 | 0.35 ± 0.05 | ||
20:2n-6 | 0.61 ± 0.06 | 0.15 ± 0.04d | ||
20:3n-6 | 1.22 ± 0.13 | 1.21 ± 0.15 | ||
20:4n-6 | 11.14 ± 0.59 | 14.82 ± 0.62c | ||
22:4n-6 | 2.51 ± 0.17 | 1.39 ± 0.12d | ||
22:5n-6 | 1.34 ± 0.33 | 0.08 ± 0.04c | ||
n-3 | ||||
18:3n-3 | ND | ND | ||
20:5n-3 | 0.15 ± 0.04 | 0.66 ± 0.09d | ||
22:5n-3 | 2.68 ± 0.18 | 3.28 ± 0.41 | ||
22:6n-3 | 0.91 ± 0.19 | 0.37 ± 0.13b | ||
n-7 | ||||
16:1n-7 | 2.88 ± 0.40 | 3.11 ± 0.44 | ||
18:1n-7 | 3.37 ± 0.19 | 2.52 ± 0.13c | ||
n-9 | ||||
18:1n-9 | 19.73 ± 0.60 | 20.45 ± 1.26 | ||
20:1n-9 | 0.24 ± 0.03 | 0.05 ± 0.01d | ||
20:3n-9 | 0.27 ± 0.10 | 0.24 ± 0.14 |
WT, wild-type; CF, cystic fibrosis. Data are given as mean ± SEM.
Mol% = mol% of total fatty acids.
P < 0.05 comparing WT cells with CF cells.
P < 0.01 comparing WT cells with CF cells.
P < 0.001 comparing WT cells with CF cells.