Figure 6. Mycophenolic acid (MPA) inhibits proliferation in P493-6 cells (left panels) and Ramos human Burkitt's lymphoma cell line (right panels).

Cell proliferation was analyzed by using colorimetric microplate assay in which tetrazolium salt was bioreduced to orange product. Y-axis represents the absorbance measurement at 450 nm. Error bars represent standard deviations derived from three independent measurements. (A) Growth rates of P493-6 cells at different concentrations of MPA. (B) Growth rates of MPA-treated P493-6 cells with guanosine supplement. (C) Growth rates of Ramos cells at different concentration of MPA. (D) Growth rates of MPA-treated Ramos cells with guanosine supplement.