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. 1999 Dec 7;96(25):14372–14377. doi: 10.1073/pnas.96.25.14372

Figure 4.

Figure 4

Expression of Hox c8-lacZ is reserved by MLL. (a) MEFs from Mll+/+ and Mll−/− embryos were transfected with a Hoxc8-lacZ construct, demonstrating integration site independent regulation of Hoxc8 in stable transfectant clones. (b) Expression of human MLL (hMLL) results in the expression of the integrated Hoxc8-lacZ reporter but not the endogenous Hoxc8 locus.

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