Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Ventral markers are overexpressed in the absence of Pax6 in the early stage of pituitary development. At e12 in Rathke’s pouch, the ventral markers αGSU, GATA2, Brn4, Isl-1, and Prop-1 are overexpressed in the Pax6 mutant mice. No difference has been observed for the POMC and Nkx3.1 levels. Pitx1, a uniformly expressed pituitary marker, showed an up-regulation at the ventral site of the pouch.
