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MARs are present and conserved at the orthologous (a) human ZNF127 and (b) mouse Zfp127 loci. There are upstream and downstream MARs at each locus (a and b) and DNA sequence divergence (c) similar to that found at the IC despite the conservation of MARs. Note that the ZNF127/Zfp127 loci are intronless, with a conserved antisense gene, ZNF127AS/Zfp127as, at this locus (27, 28).
