Skip to main content
. 1999 Dec 7;96(25):14436–14439. doi: 10.1073/pnas.96.25.14436

Figure 4.

Figure 4

Models of two different mechanisms for capping telomeric repeats in the micronucleus and macronucleus. (A) Formation of a t loop by a fold-back of the telomeric DNA in a micronuclear chromosome. The single-stranded, G-rich 3′ overhang hybridizes with the C-rich chain in a proximal segment of telomere, displacing the original G-rich chain. Redrawn from Griffith et al. (5). (B) Formation of a terminal complex between heterodimeric, telomere-binding protein and the single-stranded, G-rich 3′ overhang of the telomere in a macronuclear DNA molecule. Redrawn from Froelich-Ammon et al. (18).