TABLE 1—

Statistical Power (%) to Detect a Doubling of Adverse Event Rates in Clinical Studies of Drugs, by Sample Size

Sample Size	From 5% to 10%, %	From 1% to 2%, %	From 0.1% to 0.2%, %
1 000	82	17	5
5 000	>99	80	7
10 000	>99	>98	17
50 000	>99	>99	79

Source. Ellenberg.6

Note. A statistical power of 80% or higher is generally considered acceptable.