TABLE 6.
Statistically significanta unconditional associations between antimicrobial resistance genes
| Resistance gene | Associated resistance gene | OR | 95% CI | P value |
|---|---|---|---|---|
| ant(3″)-Ia (aadA1) | blaTEM | 11.5 | 4.9-27.2 | 0.0001 |
| catI | 53.9 | 13.2-221 | 0.0001 | |
| aph(3′)-Ia | 10.0 | 4.5-22.4 | 0.0001 | |
| tet(A) | 6.2 | 2.3-16.6 | 0.0003 | |
| su11 | 52.3 | 11.7-233 | 0.0001 | |
| dhrfIb | 96.2 | 30.2-306 | 0.0001 | |
| aph(3′)-Ia | blaTEM | 22.7 | 6.6-78.1 | 0.0001 |
| catI | 9.0 | 3.5-22.7 | 0.0001 | |
| ant(3″)-Ia (aadA1) | 10.7 | 4.7-24.5 | 0.0001 | |
| tet(B) | 16.8 | 5.0-56.8 | 0.0001 | |
| su11 | 5.9 | 2.3-15.1 | 0.0002 | |
| sul2 | 17.4 | 4.2-71.6 | 0.0001 | |
| dhfrI | 18.2 | 7.1-47.2 | 0.0001 | |
| tet(A) | ant(3″)-Ia (aadA1) | 6.7 | 2.5-17.9 | 0.0001 |
| tet(B) | 0.2 | 0.1-0.5 | 0.0012 | |
| tet(C) | 8.7 | 2.4-30.7 | 0.0008 | |
| sul1 | 15.0 | 5.6-40.0 | 0.0001 | |
| tet(B) | aph(3′)-Ia | 9.5 | 3.3-27.1 | 0.0001 |
| tet(A) | 0.2 | 0.1-0.5 | 0.0008 | |
| sul2 | 25.7 | 12.0-54.8 | 0.0001 | |
| tet(C) | floR | 17.8 | 3.9-80.8 | 0.0002 |
| tet(A) | 6.4 | 2.0-20.9 | 0.002 | |
| catI | blaTEM | 7.0 | 2.8-17.8 | 0.0001 |
| aph(3′)-Ia | 8.9 | 3.6-22.0 | 0.0001 | |
| ant(3″)-Ia (aadA1) | 56.8 | 12.2-266 | 0.0001 | |
| sul1 | 83.0 | 21.3-323 | 0.0001 | |
| dhfrI | 214 | 46.3-989 | 0.0001 | |
| floR | tet(C) | 17.4 | 3.3-92.4 | 0.0008 |
| dhfrXII | 39.4 | 7.8-200 | 0.0001 | |
| sul1 | blaTEM | 5.0 | 1.9-13.4 | 0.0012 |
| catI | 96.9 | 23.4-401 | 0.0001 | |
| aph(3′)-Ia | 6.2 | 2.4-16.4 | 0.0002 | |
| ant(3″)-Ia (aadA1) | 79.3 | 14.3-441 | 0.0001 | |
| tet(A) | 16.1 | 5.4-47.9 | 0.0001 | |
| dhfrI | 27.4 | 9.9-75.4 | 0.0001 | |
| sul2 | aph(3′)-Ia | 16.5 | 3.1-87.2 | 0.0009 |
| tet(B) | 33.9 | 15.5-74.3 | 0.0001 | |
| dhfrI | blaTEM | 13.2 | 4.5-39.1 | 0.0001 |
| catI | 193 | 44.6-836 | 0.0001 | |
| aph(3′)-Ia | 16.5 | 6.6-40.9 | 0.0001 | |
| ant(3″)-Ia (aadA1) | 86.4 | 26.3-283 | 0.0001 | |
| sul1 | 23.2 | 8.4-63.7 | 0.0001 | |
| dhfrXII | floR | 32.4 | 6.5-162 | 0.0001 |
| blaTEM | catI | 7.2 | 2.7-18.9 | 0.0001 |
| aph(3′)-Ia | 22.9 | 6.7-77.7 | 0.0001 | |
| ant(3″)-Ia (aadA1) | 12.3 | 5.1-29.7 | 0.0001 | |
| sul1 | 4.8 | 1.8-12.4 | 0.0013 | |
| dhfrI | 14.6 | 4.7-44.9 | 0.0001 |
a
Only statistically significant (P < 0.004) associations are reported. A total of 207 isolates were examined.
b
As an example, isolates that were positive for the resistance gene dhfrI were 96.2 times (95% CI, 30.2 to 306; P = 0.0001) more likely to be positive for aadA1 than isolates that were dhfrI negative.