TABLE 6.
Multidrug resistance phenotypes of commensal E. coli isolates sampled across human vocation and swine production groupsa
| Multidrug resistance response | No. of multidrug-resistant E. coli isolate (% of total) samples byb:
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human vocation group
|
Swine production group
|
||||||||||
| Non-swine workers/ nonconsumers (n = 528) | Swine workers (n = 1,131) | Non-swine workers (n = 1,675) | Influent (mixed isolates) (n = 252) | Slaughter holding pigs (n = 307) | Breeding boars (n = 195) | Quarantined boars (n = 331) | Breeding/gestation females (n = 131) | Farrowing sows and piglets (n = 755) | Grower and finisher pigs (n = 1,576) | Nursery piglets (n = 368) | |
| 0 | 309 (58.52) | 747 (66.05) | 1,100 (65.67) | 158 (62.70) | 24 (33.33) | 15 (7.69) | 4 (1.21) | 20 (15.27) | 110 (14.57) | 233 (14.78) | 18 (4.89) |
| 1 | 99 (18.75) | 203 (17.95) | 295 (17.61) | 47 (18.65) | 29 (40.28) | 85 (43.59) | 67 (20.24) | 69 (52.67) | 283 (37.48) | 780 (49.49) | 120 (32.61) |
| 2 | 32 (6.06) | 67 (5.92) | 82 (4.90) | 21 (8.33) | 10 (13.89) | 46 (23.59) | 73 (22.05) | 24 (18.32) | 127 (16.82) | 284 (18.02) | 55 (14.95) |
| 3 | 45 (8.52) | 52 (4.60) | 74 (4.42) | 10 (3.97) | 4 (5.56) | 34 (17.44) | 70 (21.15) | 11 (8.40) | 141 (18.68) | 165 (10.47) | 68 (18.48) |
| 4 | 18 (3.41) | 23 (2.03) | 67 (4.00) | 8 (3.17) | 3 (4.17) | 10 (5.13) | 75 (22.66) | 7 (5.34) | 60 (7.95) | 74 (4.70) | 53 (14.40) |
| 5 | 12.00 (2.27) | 18 (1.59) | 28 (1.67) | 5 (1.98) | 1 (1.39) | 5 (2.56) | 30 (9.06) | 0 (0.00) | 13 (1.72) | 27 (1.71) | 18 (4.89) |
| 6+c | 13 (2.46) | 21 (1.86) | 29 (1.73) | 3 (1.19) | 1 (1.39) | 0 (0.00) | 12 (3.63) | 0 (0.00) | 21 (2.78) | 13 (0.82) | 36 (9.78) |
Multidrug resistance phenotypes of commensal E. coli isolates (n = 7,477 overall sample isolates) from human and swine fecal isolates (human and swine cohorts). Frequencies and percentages of multidrug-resistant E. coli isolates are presented and contrasted with those of human vocation cohorts and swine production cohorts. Isolates are compared across all unit locations and seasons.
Multidrug-resistant E. coli isolates from human samples differed significantly (χ2 = 69.9, P < 0.001) among human vocation cohorts across all levels of multidrug resistance, using m-by-n likelihood-ratio chi-square test. Likewise, the multidrug-resistant E. coli isolates from swine samples differed significantly (χ2 = 495.2, P < 0.001) among swine production groups across all levels of multidrug resistance. Both P values are not adjusted for the dependence of responses within unit locations.
Multidrug resistance to greater than six antimicrobial agents (6+) was collapsed into a single upper category.