TABLE 2.
Genotype and allele frequencies in patients with severe chronic AR of rheumatic etiology stratified according to the NYHA functional class
| MBL | No. and frequency (%) of genotype or allelea
|
|
|---|---|---|
| NYHA class I/II (n = 54) | NYHA class III/IV (n = 46) | |
| Genotype | ||
| A/A | 23 (43) | 23 (64) |
| A/O | 20 (37) | 10 (28) |
| O/O | 11 (20) | 3 (8) |
| Allele | ||
| A | 66 (61) | 56 (78) |
| O | 42 (39) | 16 (22) |
a
P was 0.02 for the presence of the A allele in the class I/II group versus the class III/IV group (OR, 0.45; 95% CI, 0.23 to 0.88). Other differences were not significant. n, number of subjects.