TABLE 2.
Antigen-induced IFN-γ secretion by PBMC from TB patients and BCG-vaccinated healthy subjects in response to complex mycobacterial antigens, MPB70, and RD1pool
| Organism or antigena | Value for IFN-γ secretion parameter by study group
|
|||||
|---|---|---|---|---|---|---|
| TB patients (n = 40)b
|
BCG-vaccinated healthy subjects (n = 30)b
|
|||||
| Median (U/ml [range]) | No. of positive subjects/no. of subjects tested | % Positive | Median (U/ml [range]) | No. of positive subjects/no. of subjects tested | % Positive | |
| M. tuberculosis | 34 (<0.4-316) | 35/40 | 88 | 53 (<0.4-335) | 28/30 | 93 |
| M. tuberculosis CF | 39 (<0.4-373) | 36/40 | 90 | 62 (3.8-285) | 29/30 | 97 |
| BCG | 42 (<0.4-357) | 37/40 | 93 | 88 (3.9-351) | 20/22 | 91 |
| MPB70 | 4.6 (<0.4-82) | 23/38 | 60 | 18 (<0.4-207) | 17/24 | 71 |
| RD1pool | 22 (<0.4-335) | 32/38 | 84 | 9.0 (<0.4-60) | 18/22 | 82 |
CF, culture filtrate.
n, number of subjects.