TABLE 1.
Median serum antibody titers in 90 healthy individuals and 25 patients with brucellosis on admission and 1, 3, 6, and 12 months after therapy
| Test | Titera [range (median)] for:
|
|||||
|---|---|---|---|---|---|---|
| Blood donors (n = 90) | Patients at:
|
|||||
| Admission (n = 90) | 1st mo (n = 25) | 3rd mo (n = 25) | 6th mo (n = 25) | 12th mo (n = 21) | ||
| Titrated RB | 0-1:2 (0) | 1:1-1:64 (1:16) | 1:1-1:128 (1:4) | 1:1-1:64 (1:2) | 1:1-1:32 (1:1) | 1:1-1:16 (1:1) |
| MAT | 0-1:40 (0) | 1:160-1:40,960 (1:2,560) | 1:20-1:20,480 (1:640) | 0-1:10,240 (1:320) | 0-1:5,120 (1:160) | 0-1:320 (1:80) |
| Coombs test | NDb | 1:1,280-1:81,920 (1:10,240) | 1:64-1:655,360 (1:5,120) | 1:320-1:163,840 (1:5,120) | 1:80-1:81,920 (1:2,560) | 1:40-1:40,960 (1:2,560) |
| Brucellacapt | 0-1:80 (0) | 1:320-1:81,920 (1:20,480) | 1:320-1:40,960 (1:2,560) | 1:80-1:20,480 (1:640) | 1:40-1:10,240 (1:640) | 1:40-1:5,120 (1:640) |
| IgG ELISA | 1-9 (1) | 5-263 (73) | 6-336 (104) | 8-265 (88) | 8-292 (58) | 2-156 (65) |
| IgM ELISA | 1-5 (1) | 1-105 (47.5) | 2-149 (16) | 2-83 (22) | 2-56 (8.5) | 1-14 (6) |
| IgA ELISA | 2-18 (2.5) | 14-1,320 (164.5) | 8-1,419 (111) | 5-1,422 (69.5) | 5-1,040 (53.5) | 6-274 (62) |
a
Dilution titers for the titrated Rose Bengal test (RB), MAT, Coombs test, and Brucellacapt; units for ELISAs.
b
ND, not done.