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Estimated curve of protection against culture-confirmed clinical infection with wild-type influenza virus versus cell-mediated immune responses for all subjects (pooled). P(protection) is the estimated probability of being protected against clinical culture-confirmed influenza virus infection. The estimated protection curve (solid line) is charted with 95% CI (dashed lines) against the magnitude of the CMI response as determined using the number of IFN-γ SFC per 106 PBMC/ml.
