TABLE 5.
IFN-γ responses of children aged 6 to <36 months to influenza virus following vaccination
| Vaccine | A/H1N1
|
A/H3N2
|
B
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Day 6
|
Day 13
|
Day 6
|
Day 13
|
Day 6
|
Day 13
|
|||||||
| na | MFRb (95% CI) | n | MFR (95% CI) | n | MFR (95% CI) | n | MFR (95% CI) | n | MFR (95% CI) | n | MFR (95% CI) | |
| CAIV-T 107 | 8 | 7.15 (1.00, 303.0) | 5 | 55.0 (37.0, 227.0) | 7 | 1.00 (1.00, 30.0) | 4 | 36.5 (3.94, 193.0) | 6 | 3.00 (1.00, 20.0) | 4 | 73.5 (1.00, 237.0) |
| CAIV-T <105 | 7 | 1.00 (1.00, 1.18) | 10 | 1.00 (1.00, 1.00) | 7 | 1.00 (0.67, 1.00) | 7 | 1.00 (1.00, 1.00) | 3 | 1.00 (1.00, 10.0) | 4 | 1.00 (1.00, 7.00) |
| TIV | 7 | 1.00 (1.00, 29.0) | 9 | 3.00 (1.00, 5.67) | 6 | 2.00 (1.00, 3.00) | 6 | 2.50 (1.00, 41.3) | 2 | 1.00 (1.00, 1.00) | 2 | 1.00 (1.00, 1.00) |
| Placebo | 6 | 1.00 (1.00, 1.00) | 6 | 1.00 (0.50, 1.00) | 6 | 1.00 (1.00, 1.00) | 4 | 1.00 (1.00, 1.00) | 3 | 1.00 (0.08, 1.00) | 3 | 1.00 (1.00, 1.00) |
a
Number of subjects in the analysis. This number was largely dependent on the number of subjects with sufficient blood volume drawn to enable the conduct of the assay.
b
MFR, median fold rise in the postvaccination compared with the prevaccination sample.