TABLE 1.
Predicted open reading frames and pfam matches of giardial SL metabolic genesa
| Giardial open reading frame | GenBank accession no. | Match with pfam (motif location) | Species with best BLASTp match (E value) | pfam family match |
|---|---|---|---|---|
| SPT-1 | XP_779228 | 0.00012 (amino acids 137 to 523) | Danio rerio | Aminotransferase classes I and II |
| SPT-2 | XP_767472 | 6e−36 (amino acids 154 to 503) | Aspergillus terreus (6e−76) | Aminotransferase classes I and II |
| GlcT-1 | XP_767155 | 5.2e−05 (amino acids 148 to 256) | Arabidopsis thaliana (9e−30) | Glycosyltransferase family 2 |
| Smase B | XP_768146.1 | 2.4e−05 (amino acids 18 to 273) | Xenopus tropicalis (1e−25) | Calcineurinlike phosphoesterase |
| Smase 3b | XP_770759.1 | No match | Danio rerio (6e−19) | No match |
a
Five putative genes encoding SL metabolic enzymes were identified in Giardia using the NCBI and pfam databases.