Table 1.

Plasma chemistry parameters in GKRP-mutant mice fed a high-sucrose/high-fat diet

Plasma analysis	Wild type	Mutant
Glucose, mg/dl	151.0  ± 10.0	232.0  ± 25.0*
Insulin, μU/ml	10.8  ± 1.8	20.8  ± 3.6*
Lactate, mg/dl	21.4  ± 1.8	41.7  ± 5.1*
NEFA, meq/1	1.2  ± 0.1	1.2  ± 0.1
Triglycerides, mg/dl	169.0  ± 15.3	161.0  ± 15.0

Eleven-week-old male mice, at week 7 on a high-sucrose/high-fat diet, were fasted for 16 hr. Data are presented as mean ± SEM. n = 5 for wild type; n = 5 for mutant. μU, microunit; NEFA, nonesterified fatty acid. *, Differences from wild type were considered statistically significant at P < 0.05.