FIG. 1.
Hfq is required for effective UPEC colonization of the urinary tract. (A and B) Adult female CBA/J mice were infected with 108 CFU of UTI89 or UTI89 Δhfq via transurethral catheterization. Bacterial titers in bladder (A) and kidney (B) homogenates were determined at the indicated times postinoculation. Horizontal bars indicate median values for each group. WT, wild type. (C) The graph shows total numbers of IBCs per bladder at 6 h postinoculation of CBA/J mice with either UTI89 or UTI89 Δhfq. Bars denote mean values. The indicated P values were determined using the Mann-Whitney U test (n = 7 or 8 mice per group).