TABLE 3.

S. enterica serovar Typhimurium entry into the blood and brains of BALB/c mice depending on the route of inoculation^a

Strain and no. of CFU (route)	Presence in blood		Presence in brain
	1 hpib	3 hpi	24 hpi	72 hpi
Wild-type χ3761
0.7 × 109-1.2 × 109 (oral)	4/12c	1/12	2/12	4/12
1.1 × 106-1.2 × 106 (i.n.)	2/6	0/6	2/6	4/6
7.0 × 108 (i.n.)	0/6	0/6	1/3	2/3
1.1 × 103-1.2 × 103 (i.p.)	5/6	6/6	0/6	6/6
7.0 × 108 (i.p.)	6/6	6/6	3/3	Dead
Attenuated strain χ9558(pYA4088)
0.62 × 109-1.3 × 109 (oral)	3/6	1/6	0/6	0/6
0.62 × 108-1.3 × 108 (i.n.)	3/6	2/6	0/6	0/6
0.62 × 106-1.3 × 106 (i.p.)	4/6	2/6	0/6	0/6

^aThe methods used are described in Materials and Methods.

^bhpi, hours postinoculation.

^cEach value shown is the number positive/total.