Table 1.
PETs identified by SAGE
| Gene | Tag sequence | p53 wt, no. | p53 mut, no. | Unigene | Description |
|---|---|---|---|---|---|
| PET-1* | CATGAGCTAAGTTT | 25 | 0 | 19447 | ESTs |
| PET-2* | CATGCCTGACCAGG | 20 | 0 | 150378 | ESTs |
| PET-3* | CATGGTGCTGGTGC | 17 | 0 | 9613 | ESTs |
| PET-4* | CATGCCTGGACGCT | 13 | 0 | ESTs | |
| PET-5* | CATGGGAGAATTTT | 13 | 0 | 115274 | ESTs, highly similar to hedgehog (Homo sapiens) |
| PET-6* | CATGTCCTGTAAAG | 13 | 0 | 74034 | H. sapiens clone 24651 mRNA sequence |
| PET-7* | CATGTACCCAGGGC | 12 | 0 | 101395 | ESTs |
| PET-8* | CATGGCCCTGACCT | 22 | 1 | 97871 | ESTs |
| PET-9* | CATGGTGCTGCTCC | 11 | 0 | 7936 | ESTs |
| PET-10† | CATGCCGTCTTTCC | 12 | 0 | No match | |
| PET-11* | CATGGCGAGCTGGC | 12 | 0 | 146344 | ESTs |
| PET-12† | CATGACAACTTAAA | 11 | 0 | No match | |
| PET-13* | CATGCACACACCAG | 11 | 0 | 22824 | ESTs |
| PET-14† | CATGGGCCGGGCAC | 11 | 0 | No match | |
| PET-15† | CATGTGCGCTGGCC | 11 | 0 | No match | |
| PET-16† | CATGCCTTCCAGCT | 15 | 1 | No match | |
| PET-17† | CATGTTTTGCTTTT | 15 | 1 | No match | |
| PET-18† | CATGGCAGTGGGCT | 21 | 2 | No match | |
| ET2* | CATGCCTCAGCCAG | 22 | 0 | 1407 | Endothelin 2 |
| Cav* | CATGTGGATCAACC | 20 | 0 | 119333 | Caveolin, caveolae protein, 22 kDa |
| Htk* | CATGTCTGTTTCCA | 16 | 0 | 155227 | Human tyrosine kinase (HTK) |
| IPK* | CATGGAGGTCCTTC | 14 | 0 | 6453 | Human inositol 1,3,4-trisphosphate 5/6-kinase |
| RTP* | CATGGGACTTTCCT | 22 | 1 | 75789 | Human mRNA for RTP |
| B61* | CATGTGTACATTCT | 11 | 0 | 1624 | Ephrin-related ligand precursor I |
| DR5‡ | CATGAAATTGTTGG | 20 | 1 | 120932 | Human DR5/killer |
| Mat8* | CATGGCAGGGCCTC | 19 | 1 | 92323 | H. sapiens mRNA for MAT8 protein |
| Gpc* | CATGGCTTGTTCTC | 17 | 1 | 2699 | Glypican 1 |
| Jun-B* | CATGACCCACGTCA | 16 | 1 | 89792 | Jun B protooncogene |
| Tsp‡ | CATGGCTCGACTCAG | 32 | 2 | 87409 | Thrombospondin 1 |
| Tap1* | CATGGTGCAGGCTC | 16 | 1 | 158164 | Antigen peptide transporter |
| HO1* | CATGCGTGGGTGGG | 31 | 2 | 75967 | Heme oxygenase (decycling) 1 |
| ATDC* | CATGTTGCATATCA | 15 | 1 | 82237 | AT group D-associated protein |
| EVPL* | CATGGTGATGGGCT | 14 | 1 | 25482 | Envoplakin |
| p21‡ | CATGTGTCCTGGTT | 153 | 11 | 74984 | cdk-inhibitor |
PETs identified through SAGE analysis; 34 highly induced tags (14 bp) are shown. Columns 3 and 4 indicate the numbers of each tag in two libraries.
*
Transcripts that matched Unigene entries but had not been known to be regulated by p53.
† Previously unidentified transcripts that had no matches to Unigene entries.
‡ Previously described p53-regulated genes.