TABLE 1.
Bacterial factors significantly associated with T-cell toxicity
| Bacterial phenotype | Mean (median) % T-cell survivala | No. of strains |
|---|---|---|
| Beta toxin positive | 59.4 (61.9) | 163 |
| Beta toxin negative | 74.5 (77.1) | 42 |
| Delta toxin positive | 59.2 (61.7) | 51 |
| Delta toxin negative | 72.4 (77.7) | 154 |
| TSST-1 positive | 69.1 (72.4) | 53 |
| TSST-1 negative | 60.4 (63.6) | 151 |
| MRSA | 69.8 (77.2) | 23 |
| MSSA | 61.6 (66.1) | 183 |
| Agr type 1 | 54.2 (56.6) | 77 |
| Agr type 2 | 66.3 (70.6) | 47 |
| Agr type 3 | 68.4 (72.1) | 75 |
| CC1, CC12, CC15, CC22, CC30, CC39, CC51 | 67.69 (67.9) | 110b |
| CC5, CC8, CC9, CC16, CC25, CC45 | 55.57 (57.8) | 93c |
a
For beta toxin positive versus beta toxin negative, P < 0.001; for delta toxin positive versus delta toxin negative, P < 0.001; for TSST-1 positive versus TSST-1 negative, P = 0.009; for MRSA versus MSSA, P = 0.045; for Agr type 1 versus Agr type 2, P = 0.005; for Agr type 1 versus Agr type 3, P < 0.001; for Agr type 2 versus Agr type 3, P > 0.1; and for CC1, CC12, CC15, CC22, CC30, CC39, and CC51 versus CC5, CC8, CC9, CC16, CC25, and CC45, P < 0.001. All P values were determined by the Mann-Whitney U test.
b
CC1, n = 9; CC12, n = 6; CC15, n = 19; CC30, n = 57; CC39, n = 13; CC51, n = 6.
c
CC5, n = 12; CC8, n = 10; CC9, n = 4; CC16, n = 12; CC22, n = 17; CC25, n = 19; CC45, n = 22.