TABLE 2.
RQ-mPCR results and EM MICs in 200 pneumococcal isolatesa
| RQ-mPCR result | EM MIC distribution (no. of isolates)
|
||||||
|---|---|---|---|---|---|---|---|
| <0.5 μg/ml | 1 μg/ml | 2 μg/ml | 4 μg/ml | 8 μg/ml | 16 μg/ml | ≥32 μg/ml | |
| None | 56 | ||||||
| mef(A) only | 4 | 15 | 17 | 9 | 1 | ||
| erm(B) only | 3 | 7 | 10 | 67 | |||
| mef(A) + erm(B) | 1 | 2 | 8 | ||||
The CLSI EM MIC breakpoints for S. pneumoniae are as follows: susceptible, ≤0.25 μg/ml; intermediate, 0.5 μg/ml; and resistant, ≥1 μg/ml (7).