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. 2008 May 7;46(7):2384–2388. doi: 10.1128/JCM.00051-08

TABLE 3.

Comparison of RQ-mPCR results between in pneumococcal positive sputum samples and in S. pneumoniae isolates

Sample group and gene No. of samples Positive sputum samples by RQ-mPCR among samples with disagreement (n = 5)b
No. false positive/no. false negative % Sensitivity % Specificity
102/5F01 107/5F23 113/5F28 101/6S11 101/6D13
Samples with complete agreement 51/56a
Samples with disagreement
    lytA 51 + + + + + 0/0 100 99.3
    erm(B) 27 + FP FP 2/0 100 93.9
    mef(A) 19 FP + FP FP FP 2/0 100 94.8
    pbp1a 15 FN FP + + 1/1 94.4 97.5
    pbp2x 24 + FP FP + + 2/0 100 94.1
    pbp2b 12 + FP FP + + 2/0 100 95.6
a

That is, the number of samples in complete agreement with RQ-mPCR results in S. pneumoniae isolates/number of all samples.

b

FP, false-positive; FN, false-negative.