TABLE 2.
Viremia in control and vaccinated monkeys challenged with dengue-1 to -4 at 4 weeks postvaccination
| Vaccine | Animal | Challenge virus serotype | No. of viremic days | Range of viremic daysa | Group average (days) | Range of virus titers (log10 PFU/ml) |
|---|---|---|---|---|---|---|
| Control (CAdVax-C1) | RO4073 | 1 | 6 | 1-7 | 5.66 | 0.77-2.64 |
| RO4070 | 1 | 5 | 2-6 | |||
| RO4066 | 1 | 6 | 2-7 | |||
| RO4061 | 2 | 4 | 1-4 | 4.66 | 0.77-2.89 | |
| RO3032 | 2 | 5 | 1-5 | |||
| RO4092 | 2 | 5 | 2-7 | |||
| RO3010 | 3 | 3 | 1-3 | 5.66 | 0.77-2.58 | |
| RO3125 | 3 | 6 | 1-6 | |||
| RO4012 | 3 | 8 | 2-9 | |||
| RO3021 | 4 | 5 | 1-7 | 6.66 | 1.25-2.34 | |
| RO4162 | 4 | 8 | 1-8 | |||
| RO4028 | 4 | 7 | 1-8 | |||
| CAdVax-DenTV | RO4069 | 1 | 0 | 0 | ||
| RO4076 | 1 | 0 | ||||
| RO4018 | 1 | 0 | ||||
| RO4033 | 2 | 1 | 7 | 0.33 | 2.65 | |
| RO4020F | 2 | 0 | ||||
| RO4032 | 2 | 0 | ||||
| RO3031 | 3 | 0 | 0 | |||
| RO3065 | 3 | 0 | ||||
| RO3026 | 3 | 0 | ||||
| RO4005 | 4 | 1 | 6 | 1 | 1.17-1.73 | |
| RO3053 | 4 | 1 | 6 | |||
| RO4090 | 4 | 1 | 4 |
a
The range is the period between the days on which viremia was first and last detected.