FIG. 6.

Virulence of Y. enterocolitica serotype O:8 strains WA(pYVO8-A-0) (YadA-negative virulence plasmid carrying strain), WA(pYVO8-A-1) (YadA wild type), WA(pYVO8-YadA-UspA1), WA(pYVO8-YadA-EibA), and WA(pYVO8-YadA-Hia) in orally (A), intravenously (B), and intraperitoneally (C) infected groups of five BALB/c mice infected with 1 × 10⁹ CFU (A) or 5 × 10⁴ CFU (B and C) of bacteria. After 5 days (A) or 2 and 4 days (B and C), the CFU of bacteria in the small intestine (SI), Peyer's patches (PP), spleen (S), and liver (L) (A) or in the spleen (S) and liver (L) (B and C) were determined. The data are means ± the standard deviations. wt, wild type.