FIG. 1.

The syp cluster and the SypF protein. (A) The syp cluster contains 18 genes (sypA to -R) that encode putative polysaccharide synthesis and transport proteins as well as four putative regulatory proteins, three of which are two-component regulators. The genes that are the subject of the manuscript are shown with gray (sypE and sypG) and white (sypF) arrows, while the remaining genes are shown with black arrows. The small bent arrows above the genes indicate known and putative promoters. (B) Domain structure of the hybrid sensor kinase SypF. SypF contains conserved histidine (H250, H705) and aspartate (D549) residues typical of hybrid sensor kinases. The putative SypF1 protein contains two substitutions, S247F in the HisKA domain and V439I in the H_ATPase domain, relative to that encoded within the annotated genome.