TABLE 2.
Test for fitness differences between evolved strains and allele-replacement strains that carry all its identified mutationsa
| Competition | S (102) | Difference in S | SE | P | Outcome |
|---|---|---|---|---|---|
| GD-GA | 3.050 | 0.0042 | 0.0021 | 0.0446 | GD = rGD |
| rGD-GA | 2.625 | ||||
| GE-GD | -7.334 | 0.0048 | 0.0077 | 0.5400 | GE = rGE |
| rGE-GD | -7.128 | ||||
| GC-rGA | -6.702 | 0.0753 | 0.0041 | 7.06E-35 | GC > rGC |
| rGC-rGA | -14.351 | ||||
| GA-GC | 9.135 | -0.0245 | 0.0040 | 1.18E-08 | GA > rGA |
| rGA-GC | 6.702 |
a
S, selection rate. These experiments were done to verify whether all causative mutations had been found. Allele-replacement “reconstruction” strains are labeled rGX, i.e., for reconstruction of evolved strain GX.