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Potent inhibition of CP621-652 against T-20- and C34-resistant virus
| Peptide | Mean IC50 (nM) ± SD
|
Fold change | |
|---|---|---|---|
| NL4-3 WT | NL 4-3 V38E + N42S | ||
| T-20 | 33.86 ± 1.12 | >2,000.00 | >59.17 |
| C34 | 3.60 ± 0.38 | 82.68 ± 2.21 | 22.97 |
| CP621-652 | 4.55 ± 0.33 | 4.22 ± 0.27 | 0.93 |
| CP628-654 | >2,000.00 | >2,000.00 | |
