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. 2008 May 12;28(14):4598–4608. doi: 10.1128/MCB.02192-07

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FIG. 8. — Constitutively active β-catenin signaling in TRβ^PV/PV thyroids. Thyroid extracts of wild-type and TRβ^PV/PV mice were analyzed by Western blotting for protein abundance of several markers of β-catenin signaling activation. (A) Blots of β-catenin phosphorylated at serine residue 552 (p-β-catenin-S552) (a), total β-catenin (b), and the loading control PDI (c). (B) Protein levels of c-Myc (a), cyclin D1 (b), MT1-MMP (c), and PDI (d) in the thyroid extracts of wild-type and TRβ^PV/PV mice. Lanes are marked.