Table 2.
Demographic data, variables and outcome data; comparisons of sepsis patients with EGDT study [8] data
| Variable | Present cohort (n = 263) | Sepsis (n = 125) | EGDT study (n = 263) | p Valuea,b |
| Age (years) | 67.3 ± 14.2 | 68.9 ± 13.5 | 65.7 ± 17.2 | 0.01* |
| Female (%) | 41 | 38 | 49.4 | |
| Male (%) | 59 | 62 | 50.6 | |
| Heart rate (beats/min) | 107 ± 27 | 115 ± 26 | 115 ± 29 | 1.0 |
| CVP (mmHg) | 9.8 ± 5.4 | 10.8 ± 4.9 | 5.7 ± 8.5 | < 0.01* |
| MAP (mmHg) | 58 ± 16 | 60 ± 13 | 75 ± 25 | < 0.01* |
| ScvO2 (%) | 72.0 ± 12.3 | 74.0 ± 10.2 | 48.9 ± 12.3 | < 0.01* |
| Lactate (mmol/l) | 3.3 ± 3.3 | 2.7 ± 2.2 | 7.3 ± 4.6 | < 0.01* |
| Arterial pH | 7.33 ± 0.12 | 7.35 ± 0.10 | 7.32 ± 0.18 | 0.42 |
| Hematocrit (%) | 31.0 ± 7.0 | 30.3 ± 6.9 | 34.7 ± 8.5 | < 0.01* |
| APACHE II score | 21.5 ± 8.5 | 20.9 ± 7.3 | 20.9 ± 7.2 | 1.0 |
| SOFA score | 9.5 ± 3.6 | 9.6 ± 3.0 | ||
| In-hospital mortality (%) | 31.0 | 26.0 | ||
| Standard therapy | 46.5 | |||
| EGDT | 30.5 |
Data are presented as means ± SD. aUnpaired t test; bsepsis subgroup vs EGDT study. *Statistically significant difference. APACHE II, Acute Physiology, Age and Chronic Health Evaluation; CVP, central venous pressure; EGDT, early goal-directed therapy; MAP, mean arterial pressure; ScvO2, central venous oxygen saturation; SOFA, Sequential Organ Failure Assessment.